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Tryptamine and its derivatives that have been reported as NPS are indolealkylamine molecules. While some naturally occuring tryptamines are neurotransmitters (e.g. serotonin, melatonin and bufotenin), most are psychoactive hallucinogens found in plants, fungi and animals (e.g. N,N-dimethyltryptamine (DMT) psilocybin, and 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) [1-3].